The approach improves the function of SYNGAP1-deficient neurons in vitro, but whether it will work in people remains unclear. The post ‘Splice-switching’ strategy boosts SYNGAP1 expression appeared first on Spectrum | Autism Research News. Source: Spectrum News

Two groups of researchers respond to Spectrum’s article about the power struggle among researchers, self-advocates and families, calling on their autistic and non-autistic colleagues to work collaboratively and promote equity in autism research. The post Letter to the editor: Researchers must bridge…

Researchers took to Twitter this week to discuss the most complete map of brain structure to date — that of a larval fruit fly — and the largest-yet human brain connectivity resource. The post Community Newsletter: Tracing fruit fly, human connectomes appeared first on Spectrum | Autism …

Here is a roundup of news and research for the week of 13 March. The post Spotted around the web: Brain imaging replicability; CRISPR-edited neurons; sex-based variability in mice appeared first on Spectrum | Autism Research News. Source: Spectrum News

The tool connects to electrodes implanted in people with epilepsy or other brain conditions and can monitor and regulate neurons during everyday activities. The post Wearable device records, stimulates single neurons in people on the go appeared first on Spectrum | Autism Research News. Source: Spe…

In this edition of Null and Noteworthy, Spectrum talks with a Nature editor about the journal’s move to publish more null results. The post Null and Noteworthy: Registered reports; motor measurements; viral DNA appeared first on Spectrum | Autism Research News. Source: Spectrum News

The drug, welcomed by patients, might be just the first of many. The post FDA approval of trofinetide may spur further drug development for Rett appeared first on Spectrum | Autism Research News. Source: Spectrum News

The most comprehensive study of neurodevelopmental conditions in Kenya and South Africa ever conducted shares preliminary results and lessons. The post African genetics study NeuroDev shares initial findings appeared first on Spectrum | Autism Research News. Source: Spectrum News

The Modified Checklist for Autism in Toddlers (M-CHAT) accurately flags autistic toddlers, a new systematic review and meta-analysis suggests, contrary to past evidence that the tool’s validity varies depending on a child’s age and traits. Experts weigh in on the discrepancy. The post Journal Club: …

Methodological choices and study-site artifacts confounded an attempt to replicate findings in support of an autism brain-imaging biomarker, according to new unpublished work. The post Brain imaging do-over offers clues to field’s replication problem appeared first on Spectrum | Autism Research News…