Some conditions are too rare for conventional drug trials, leading some scientists to test bespoke treatments in single participants. Gleeson discusses the merits — and limitations — of these tiny trials. SourceSource: Spectrum News

This month’s issue of the Going on Trial newsletter examines personalized therapies for rare conditions, Acadia’s new drug for Rett syndrome and developments in a cord-blood program, among other autism-related drug trial news. SourceSource: Spectrum News

Evidence of measurement bias undermines past claims about autistic children’s lower well-being. SourceSource: Spectrum News

Studies of behavioral treatments for autism are complex and can easily be misunderstood. Here we provide some guidance. SourceSource: Spectrum News

Male rats prenatally exposed to a maternal immune response have atypical responses to other rats in distress, according to a new study. SourceSource: Spectrum News

Discussion on social media revolved around a meta-analysis of suicidality in autism, a method to purify neural stem and progenitor cells, and autism-linked genes in zebrafish. SourceSource: Spectrum News

Here is a roundup of news and research for the week of 20 March. SourceSource: Spectrum News

People whose brains look like those of people who carry autism-linked copy number variants also share markers of heart health. SourceSource: Spectrum News

About 1 in 36 children in the United States has autism, up almost 20 percent from the previous estimate, reflecting improved identification, particularly among girls and Black, Hispanic and Asian or Pacific Islander children. SourceSource: Spectrum News

Cannabidiol (CBD) blocks the action of a molecule that drives an overexcitability feedback loop in a rodent model of epilepsy. The post Cannabis compound rebalances signaling to quell seizures in mice appeared first on Spectrum | Autism Research News. Source: Spectrum News

The approach improves the function of SYNGAP1-deficient neurons in vitro, but whether it will work in people remains unclear. The post ‘Splice-switching’ strategy boosts SYNGAP1 expression appeared first on Spectrum | Autism Research News. Source: Spectrum News

Two groups of researchers respond to Spectrum’s article about the power struggle among researchers, self-advocates and families, calling on their autistic and non-autistic colleagues to work collaboratively and promote equity in autism research. The post Letter to the editor: Researchers must bridge…

Researchers took to Twitter this week to discuss the most complete map of brain structure to date — that of a larval fruit fly — and the largest-yet human brain connectivity resource. The post Community Newsletter: Tracing fruit fly, human connectomes appeared first on Spectrum | Autism …

Here is a roundup of news and research for the week of 13 March. The post Spotted around the web: Brain imaging replicability; CRISPR-edited neurons; sex-based variability in mice appeared first on Spectrum | Autism Research News. Source: Spectrum News